- 2014 University California San Francisco (UCSF) 의과대학 방문교수
, academicCareer=, researchField=
- 암 관련분야
- 생식의학, 발생학, 줄기세포
- 세포성장조절, 노화
- 동물질병진단
, lectureField=
- 실험동물의학
- 동물임상병리학 및 실습
, thesis=
주요논문
- Coenzyme Q10 ameliorates the quality of mouse oocytes during in vitro culture. Zygote. 2020
- The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle. Scientific Reports. 2017
- Maternal mRNAs with distinct 3' UTRs define the temporal pattern of Ccnb1 synthesis during mouse oocyte meiotic maturation. Genes and Development. 2017
- Oocyte Maturation Process of Zebrafish (Danio rerio), an Emerging Animal Model. Journal of Life Science. 2015
- Wee1B Is an Oocyte-Specific Kinase Involved in the Control of Meiotic Arrest in the Mouse. Curr Biol. 2005
- Choi C, et al. A collaborative study to establish the second national standard for hepatitis B immunoglobulin in Korea. Biologicals (2023)
- Choi C, et al., Collaborative study for the establishment of National Reference Standard for Molecular Size Distribution Test of Human Immunoglobulin Products. Yakhak Hoeji (2021)
- Kim J, et al., Development of a rabbit monocyte activation test as an alternative to the rabbit pyrogen test and its application in the analysis of plasma-derived products. Biologicals (2021)
- Choi C, et al., Standardization and validation of molecular size distribution test for human immunoglobulin products in Korea. Yakhak Hoeji (2021)
- Han K, et al., Standardization of the first Korean national reference standard for snake (Gloydius brevicaudus) antivenom. Toxicol Res (2020)
- Han K, et al., A Collaborative Study to Establish the Second Korean National Reference Standard for Snake Venom. Toxicol Res (2018)
- Oh H, et al., The 2nd Meeting of National Control Laboratories for Vaccines and Biologicals in the Western Pacific. Osong Public Health Res Perspect (2018)
- Park T, et al., Stability Evaluation of National Reference Standards for Blood Products in Korea. Toxicol Res (2017)
- Oh H, et al., The first Meeting of National Control Laboratories for Vaccines and Biologicals in the Western Pacific in 2016. Osong Public Health Res Perspect (2017)
- Han K, et al., Differential Expression of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Open Reading Frame 5, but not Apoptogenic Cytokines, Contribute to Severe Respiratory Disease in Pigs Infected with Type 2 PRRSV Compared with Pigs Infected with Type 1 PRRSV. J Comp Pathol (2016)
- Han K, et al., Vaccination of sows against type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) before artificial insemination protects against type 2 PRRSV challenge but does not protect against type 1 PRRSV challenge in late gestation. Vet Res (2014)
- Han K, et al. Comparative virulence of reproductive diseases caused by type 1 (European-like) and type 2 (North American-like) porcine reproductive and respiratory syndrome virus in experimentally infected pregnant gilts. J Comp Pathol (2014)
- Han K, et al. Comparison of the virulence of European and North American genotypes of porcine reproductive and respiratory syndrome virus in experimentally infected pigs. Vet J (2013)
- Han K, et al. Comparative Pathogenicity of Three Korean and One Lelystad Type 1 Porcine Reproductive and Respiratory Syndrome Virus (Pan-European Subtype 1) Isolates in Experimentally Infected Pigs. J Comp Pathol (2013)
- Han K, et al. Comparative pathogenesis of type 1 (European genotype) and type 2 (North American genotype) porcine reproductive and respiratory syndrome virus in infected boar. Virology J (2013)
- Han K, et al. Pathogenesis of Korean Type 1 (European Genotype) Porcine Reproductive and Respiratory Syndrome Virus in Experimentally Infected Pregnant Gilts. J Comp Pathol (2013)
- Han K, et al. Pathogenesis of type 1 (European genotype) porcine reproductive and respiratory syndrome virus in male gonads of infected boar. Vet Res Commun (2013)
- Han K, et al. Efficacy of a piglet-specific commercial inactivated vaccine against Porcine circovius type 2 in clinical field trials. The Canadian Journal of Vet Res (2013)
- Han K, et al. Evaluation of monoclonal antibody–based immunohistochemistry for the detection of European and North American Porcine reproductive and respiratory syndrome virus and a comparison with in situ hybridization and reverse transcription polymerase chain reaction. J Vet Diagn Invest (2012)
- Han K, et al. Effects of North American Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)-Based Modified Live Vaccines on Preimmunized Sows Artificially Inseminated with European PRRSV-Spiked Semen. Clin Vaccine Immunol (2012)
- Han K, et al. Pathogenesis of Korean Type 1 (European Genotype) Porcine Reproductive and Respiratory Syndrome Virus in Experimentally Infected Pigs. J Comp Pathol (2012)
- Han K, et al. Effect of the Modified Live Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Vaccine on European and North American PRRSV Shedding in Semen from Infected Boars. Clin Vaccine Immunol (2011)
- 2001-2005 하버드의과대학 및 브리검여성병원 (post-doc research fellow)
- 2005- 현재 인제대학교 교수(작업치료학과 및 반려동물보건학과 )
, academicCareer=
- 한국뇌신경과학회(정회원)
- 한국발생생물학회(편집위원)
- 대한고령자치매작업치료학회(이사)
- 한국분자세포생물학회(정회원)
- 김해시 수의사회 회원
, researchField=
- 재활분야에서 동물매개 치료 활용에 대한 연구 (2023년도 교내연구비(연구년) 선정)
- 인공지능 모션영상분석을 통한 손기능 평가법 개발 (반려동물행동분석에 응용)
- 토픽모델링과 텍스트 네트워크 분석을 통한 반려동물산업 동향 분석
, lectureField=
반려동물학, 동물해부생리학 및 실습, 동물질병학
, thesis=
저서
- 원리중심의 인체생리학(라이프사이언스, 2022)
- 사람해부학(에듀팩토리, 2020)
- 알기쉬운 병리학(메디컬사이언스, 2019)
- 신경과학: 뇌의탐구(바이오메디북, 2018)
주요논문
- Effects of Apolipoprotein E ɛ4 and Risk Factors on Domains of Cognition in Mild Cognitive Impairment and Dementia. Journal of Alzheimer’s Disease, in press.
- 모션인식을 이용한 수부재활이 수부손상환자의 손기능에 미치는 영향. 한국산학기술학회지, 2021.
- Correlation of Hand Function Differences and Brain Preference:Focusing on Young Adults. Annals of the Romanian Society for Cell Biology, 2021.
- Effect of dihydroferulic acid obtained from fermented rice bran extract on neuroprotection and behavioral recovery in an ischemic rat model. Food Science and Technology(Campinas), 2020
- Anti-inflammatory effect of water extracts obtained from doenjang in LPS-stimulated RAW 264.7 cells. Food Science and Technology(Campinas), 2019
- Evaluation of antioxidant activities, total phenolic content (TPC), and total catechin content (TCC) of 10 sugar apple (Annona squamosa L.) cultivar peels grown in Thailand. Food Science and Technology(Campinas), 2018
- Retrogradation of heat-gelatinized rice grain in sealed packaging: investigation of moisture relocation. Food Science and Technology(Campinas), 2016
- Neuroprotective effect of rice bran extract supplemented with ferulic acid in the rat model of ischemic brain injury. Animal Cells and Systems, 2014
- Companion animal-based translational research for cancer research
- Establishment of human immune system mouse
- Regulation of tumor-stromal interaction and its influence in the T cell-mediated antitumor immunity
- Development of combination strategies to enhance cancer therapeutic potentials
, lectureField=
반려동물학, 의약품관리학, 실험동물의학
, thesis=
1. Lee HK, Na YJ, Seong SM, Ahn D, Choi KC Cordycepin enhanced therapeutic potential of gemcitabine against cholangiocarcinoma via downregulating cancer stem-like properties. Biomol Ther 2024 May 1;32(3):369-378. First Author
2. Choi Y,LeeHK,Ahn D, Nam MW, Go RY, Choi KC. Genetically engineered neural stem cells expressing cytosine deaminase and interferon-beta enhanced T cell-mediated antitumor immunity against gastric cancer in a humanized mouse model. Life sciences 2023 Sep 1;328 121866 Co-First Author
3. Nam MW,LeeHK,Kim CW, Choi Y, Go RY, Choi KC. Effects of CCN6 overexpression on the cell motility and activation of p38/bone morphogenetic protein signaling pathways in pancreatic cancer cells. Biomedicines & Pharmacotherapy 2023 Jul, 163, 114780 Co-First Author
4. Lee HK, Nam MW, Go RE, Koo JH, Kim TH, Park JE, Choi KC. TGF-β2 antisense oligonucleotide enhances T-cell mediated anti-tumor activities by IL-2 via attenuation of fibrotic reaction in a humanized mouse model of pancreatic ductal adenocarcinoma. Biomedicines & Pharmacotherapy 2023 Mar, 159, 114212 First Author
5. Lee HK, Kim CW, Ahn DH, Go RE, Choi YD, Choi KC. Next-generation antisense oligonucleotide of TGF-β2 enhances T cell-mediated anticancer efficacy of anti-PD-1 therapy in a humanized mouse model of immune-excluded melanoma. Cancers 2022, 14(21), 5220
- 비타민C 및 E 급여가 한우거세우의 도체특성 및 육질에 미치는 영향. 2004 (석사)
- Studies on the Improvement of Phosphorus and Zinc Availabilities by Phytases in Growing Pigs. 2008 (박사)
- Effects of dietary addition of wormwood on growth performance, blood characteristics and meat quality in growing-fattening pigs. 2022. Czech Journal of Animal Science (주저자)
- Efficacy of fermented carrot by-product diets on blood profiles, immune responses, and faecal characteristics in fattening pigs. 2023. Animal Production Science (주저자)
- Effect of supplementation of rumen-protected choline with soluble vitamins on hepatic function and carcass characteristics in Hanwoo steers. 2023. Journal of Animal and Feed Sciences (주저자)
- Effects of fermented carrot by-product diets on growth performances, carcass characteristics and meat quality in fattening pigs. 2023. Acta Agriculturae Scandinavica, Section A (주저자)
- 2019~2021. Harvard Medical School-BIDMC Hem/Onc (Visiting Scholar)
- 2015~현재 인제대학교 생물안전위원회(IBC) (위원장)
- 2015~2017 인제대학교 동물자원센터 (센터장)
- 2014~2019 인제대학교 바이오헬스 소재 연구센터(BPRC) (센터장)
- 2014~2016 인제대학교 u-항노화 헬스케어 연구소(u-HARC) (연구소장)
- 2011~2013. Harvard Medical School-BIDMC Pathology (Research Associate)
- 2001~2004 UT-Southwestern Medical Center (Post-doctoral fellow)
- 2004~현재 인제대학교 교수 (물리치료학과 및 반려동물보건학과 )
, academicCareer=
- 대한라이프스타일의학회 학술위원장
- 대한고령친화산업학회지 편집위원장
- 대한수의학회, 대한생화학회 정회원
- 미국생화학회, 미국생리학회, 미국신경학회 정회원
- 대한생명과학회 이사
, researchField=
- 동물 매개 치료: 반려동물을 이용한 퇴행성 뇌질환 및 퇴행성 근골격계질환 치료법 개발
- 마이크로바이옴: 반려동물 유래 인체 마이크로바이옴 연구
- 진단키트 및 치료제 개발: 극초기 퇴행성 뇌질환 및 근골격계질환 진단키트 개발
, lectureField=
- 의약품관리학 및 실습
- 동물공중보건학
- 동물매개 퇴행성질환 치료
- 생활습관병과 반려동물
, thesis=
저서
- 보건기초 생물학 (도서출판 고려의학, 2022)
- 생리학 학습서 (라이프사이언스, 2019)
- 머크매뉴얼(제20판) (도서출판 신일북스, 2019)
- Fitzgerald’s 임상신경해부학 및 신경과학 (범문에듀케이션, 2017)
- 기본 동물해부생리학 (라이프사이언스, 2015)
논문
- Hong Y. et al. Pre- and post-conditioning with poly I:C exerts neuroprotective effect against cerebral ischemia injury in animal models: a systematic review and meta-analysis. CNS Neuroscience & Therapeutics 2022. 26(7):1~15.
- Hong Y. et al. Neurodegenerative effect of DAPK1 after cerebral hypoxia-ischemia is associated with its post-transcriptional and signal transduction regulations: A systematic review and meta-analysis. Ageing Research Reviews. 2022. 76:1~25.
- Hong Y. et al. Neurocognitive effects of melatonin treatment in healthy adults and individuals with Alzheimer’s disease and insomnia: a systematic review and meta-analysis of randomized controlled trials. Neuroscience & Biobehavioral Reviews. 2021. 127(1):459~473.
- Hong Y. et al. Differential role of melatonin in healthy brain aging: a systematic review and meta-analysis of the SAMP8 model. Aging-US. 2021. 13(7):9373~9397.
- Hong Y. et al. The comprehension of composition, diversity, related diseases, and treatment of the gut microbiome in companion Dogs: Friend or Foe? Life Sciences. 2020. 30(11):1021~1032.
- Hong Y. et al. Evaluation of cognitive function in adult rhesus monkeys using the finger maze test. Applied Animal Behaviour Science. 2020. 224(104945):1~5.